Longevity-Associated Triglycerides (7-Test Results)

Published 2024-05-05
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Papers referenced in the video:
Serum Cholesterol and Impact of Age on Coronary Heart Disease Death in More Than 4 Million Veterans pubmed.ncbi.nlm.nih.gov/37889207/

Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals www.nature.com/articles/s41467-023-41515-z

All Comments (19)
  • It’s estimated that upwards of 80% of American adults are metabolically unhealthy so using them as a basis for comparison makes no sense.
  • @DavidPodolsky
    Excellent video. So many markers to track, though. Mike, in addition to the 25-30 or so blood markets you always present in your summary tables, and in addition to RHR, AHR, HRV, Vo2max, and strength, what would be your recommended top 3-5 or so biomarkers to track? I appreciate your points of view. I don't yet track NAD, telomeres, etc., but it is hard to know how to prioritize.
  • @Maple597
    I noticed that creatine is also identified in the upper left quadrant. Does this mean supplementing with creatine will increase the odds of living to 85?
  • Thx prof.Lustgarten for this another great analysis. In terms of mortality، very probably the health benefit of maintaining glycerides levels under 40-50 mg/dL more than compensate for the risk of having those longevity promoting triglycérides , whose lab assessment is maybe costly and not available in certain countries, at a high level ?
  • @doughughes257
    At 1:20 in the video, the graph shows three labeled triglycerides(C56:8, C58:11, C58:7) that were not part of your tracking later. Why was that?
  • triglycerides are synthsized from carbohydrates (diet)? High intake of starchy foods.
  • @monnoo8221
    I really don't get it. Firs, what is the meaning of plotting longevity against all cause mortality, as one can be expressed by the other? If doing that at all, the deviance from the regression line is telling something for this plot. otherwise longevity or ACM alone is completely sufficient. I also do not understand the IOLLO way of counting to 3 . They indicate Tri-AcylGlycerides as 56:6, for instance, but then they list only 2 fatty acids, which yield the some of the respective species. Can you please help me out here? Finally, given what we know - and not know - about fatty acids metabolism, I think summing up across the "species" is not correct. I suggest to analyze each subtype for its own. Would you agree?
  • @ManlioLoGiudice
    Another excellent one! Ill reach out to set up a podcast with you soon!
  • @jamesgilmore8192
    Does anyone know if any specific saturated fatty acid has been associated with lower all cause mortality?
  • @carlov5740
    Hi Michael, I was curious to know what's your take on IF. Prof Fontana seems to stress that has to be done carefully as recent association stusies seems to caution on a generalised one size fit all IF. Meanwhile Prof Longo recently maintained that 12hrs IF routine is safe. Obviously these views are not mutually exclusive but I was wondering what's your take on this issue? thanks a lot
  • @AndroidSon
    Just eat like some clever russian siberians eat: 1. Milk porige with broken whole oatmel or wheat grain for breakfast at 7-8 in morning. GHI butter for garnish. 2, Some any dish with a meat and any garnish you want for dinner at 12-13 in middday. 3. All by one the onion, potato, carrot, beat and some cabbage chopped and boiled 30 minutes in some water and some wegetable oil added for supper at 17-18 in evening. And nothing else till next morning. All food must be not processed. Try it for nice health and no doctor to call.