Taurine: The Nutrient of Youth [Science Explained]

3 Things: 1. On a quick search (I haven’t looked into this deeply), taurine seems to reduce or attenuate increases in cholesterol lipoproteins according to a meta-analysis (DOI: 10.1016/j.ejphar.2020.173533). So, as I suspected, it isn’t much of a worry (I’ll need to confirm this) - yet the association with increased blood levels is still a mystery - why do you think it might be the case? Let’s take some guesses! 2. And, apparently I see 'orange' as 'red', yet I'm not color blind.. 3. @6:43 - that should read 'SASP', not 'SAPS'.

I worked in health care for 33 years. The first 13 of those years was in a seniors' nursing home. I have seen residents who lived to be well into their 90's but were wheelchair bound since they were 70. Longevity IS NOT the preferred outcome (unless you are scared to die I suppose), but rather quality of life. Living to be 85 years old while still being active, independent, mobile, mostly free of pain and living and loving those you care about is the goal. When I look at these sorts of studies, I am interested in longevity potential but I key in on those aspects that imply a better quality of life, i.e. hirer bone density from Taurine supplementation.

Maybe our lives won’t be extended to a significant degree but taurine may help improve quality of life in our later years.

Highlights 💡 Taurine supplementation increased lifespan by 10-12% in mice. 💡 Taurine supplementation reduced body fat, improved muscle strength, and blood sugar levels. 💡 Taurine showed potential in reducing senescent cells and increasing stem cells. 💡 The study suggests that taurine can be beneficial later in life, even if not taken in the earliest stages. 💡 While there are some potential negatives associated with taurine, further research is needed to fully understand its effects in humans.

well done. years ago, i found a book where a woman claimed to cure her asthma using vits a(retinol), c and e. it worked for me too. then it stopped working. but i noticed it worked after i'd eaten a tin of smoked oysters. i worked out it was the high level of taurine in oysters that was what enabled my body to make use of oil-based vitamins like retinol and vit e through the production of gall. i hope this information helps.

My vet recommended it for my dying dogs heart and he lived months longer than predicted.

Very informative video. I am a 64 year old male. I started taking a Taurine 500mg supplement about 3 months ago. I have been getting better sleep. I have also noticed more energy. My sleep is more restful and deep. My energy has slightly increased. I plan to continue to take Taurine.

Taurine caused my dogs cataract to go away. It came back years later but Taurine again helped. My kitty was literally dying of heart disease. L Taurine brought him back and he lived quite some time after that.

I'm practically a 5 year old when it comes to these topics so I appreciate being taught this way! Thank you

One of the biggest problems with mouse studies, apart from the obviously massive gap in genetic makeup, is that their standard laboratory diet is extremely poor and unnatural. They are fed primarily corn and soy, both usually GMO. So basically any change in diet, or supplementation, may show an improvement where a more natural baseline diet would not. We just don’t know. That’s also how fad diets get started in human populations: the standard American diet is so poor in nutrients and rich in pollutants that almost any change will yield improvements.

I'm 44 years old, and I take taurine every day. I've been working in shifts for 18 years. Taurine is a salvation for my sleep, and as I train every day, strength and cardio it helps a lot to endure shifts, sleeping during the day and daily physical exercise.

Based on the content of the video, here's a summary of the key points discussed regarding the study on taurine and its potential effects on lifespan, health span, stem cells, and cellular senescence: 1. *Lifespan and Taurine Levels:* - The study measured taurine levels in blood across different biological systems, including mice, monkeys, and humans. - In humans, taurine levels decrease with age, with a significant reduction by age 50. - Mice were fed either a taurine-supplemented or non-supplemented diet. Those supplemented with taurine had a 10-12% longer lifespan compared to the non-supplemented group. - Notably, taurine supplementation began in middle age for the mice, suggesting its benefits can still be realized later in life. 2. *Metrics of Health Span:* - Taurine supplementation led to reduced body fat, improved muscle strength, and better blood sugar levels. - Bone health was positively impacted, with increased bone volume and improved bone strength observed in taurine-supplemented groups. 3. *Stem Cells and Cellular Senescence:* - Stem cells are crucial for healing and defense against pathogens, while senescent cells can negatively affect surrounding cells. - Taurine supplementation was associated with reduced cellular senescence markers in various tissues. - An experiment involving gene analysis suggested a potential increase in mitotically active stem cells due to taurine supplementation. 4. *Correlations and Interpretation:* - The study had animal models (mice) as well as data from monkeys and humans. - Positive correlations were found between taurine levels and various health markers, including reduced inflammation and obesity. - There were also negative correlations, such as dyslipidemia and elevated liver enzyme levels, that were not extensively discussed in the video. - The presenter emphasized the need to consider both positive and negative correlations and to avoid oversimplifying the results. 5. *Application and Implications:* - The presenter was cautious about the interpretation and emphasized the potential but speculative nature of the findings. - While taurine might not extend human lifespan by 12%, it could still have significant effects on overall health. - Taurine supplementation later in life could be impactful, potentially compensating for earlier lifestyle habits. - The presenter suggested watching their detailed study analysis for more comprehensive information on the findings.

I love that our generation is pretty much the test subjects for thousands of supplements

I'm nearing 70. As diabetic from the past (eight years on insulin after a heart attack), fasting one day a week (for 36-40 hours) led to improvement in A1C. Having been encouraged by this, I went aggressively for HFLC diet and overnight fasting (found out I 'm good at it!) with 7,000 steps everyday (sometimes within the house because of inclement weather) for over 7 months. However, I noticed I wasn't producing enough energy to go up a hill and my LdL and total cholesterol had gone up (and LdL above the range for the first time). The triglycerides remained below 80. A1C was 5.4. I had lost over 35 pounds and reached a BMI of 19.5 which worried my doctor. So I went for a week-long program (over the net) run by a famous doctor (doing research first using Atkins then Keto for over 25 years) but they were unable or unwilling to talk about how to address "low power". The course was mainly for people who had high BMI. I then went for an exercise bike after getting fooled by studies on "Italian alpine cyclists". Now after another 15 months, this June (2023), after 22 months being out of any medication for diabetes but still with "low power", I found you. You made me realize the folly of many things including "insulin resistance" for those who have no weight to lose. I had already played with relaxing the A1C to a steady state of 6.5 but now with LdL and total cholesterol both within range. I had also realized since the beginning of 2023, that one thing is autophagy but another thing is to have cell death. Lactic acid production from that "cyclist trainer" made cell death possibly worse. So I am increasingly saying: "it's the health of the mitochondria stupid". It's clear for me it’s less calorie, be it from carb or fat (that's from you - thank you), and with supplementation to reduce ROS. The Taurine study, as many of these studies go, is mainly for overweight people and those with blood sugar issues.

Since I feel having being called out I want to clarify some things: 1) the fact that I use your videos for taking naps doesn't mean I don't follow them, when I wake up I usually start again to the last thing I remember 2) it means you have a nice calming voice 3) I also use Andrew hubermann's videos for the same purpose because he has a warm calming voice.

Thank you for being truthful and nuanced while still keeping it fun, I wish we had more content creator like you, cheers

I am 69 yoa. I had been taking 1grm/day taurine for 5 years. The new study on taurine up to 6 grms/day is game changing for me. So, I have several decades more extension in my healthy lifespan.

Been taking it for 2 weeks and 3 days and on the 4th day I finally can feel the difference and I love it and feel great!

Looking forward to the second segment on Taurine supplementation.

Thank you! This just showed up in my YouTube feed, and I'm so glad it did! I've been interested in and learning as much as I can about science, especially regarding health, my entire life. My education and training has not been in the science or medical field, it's one of my favorite interests. I love learning as much as I am able, it's a passion of mine. So, Geek on! The information you share will help so many people... including people who are so inclined, as I am, are able to Geek Out with you ❤ Thank you!