Keto diet and high LDL study – Diet Doctor Podcast

Thanks for having us on, Bret. And thanks so much to everyone who has either contributed to the study directly through our charity or is participating directly in the study!

I’m so glad and thankful to be selected as one of the participants in the lean mass Hyperresponder study, started keto June 2017.❤🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️

" Bad cholesterol" The Human body would not produce something that is bad for it. Now back to my rib-eye.

Can relate to the doctor visit. Yearly check up is a month away last year my LDL was 411. You can imagine what I heard from my doctor I go through several days of stress afterwards.

I am so happy to see another engineer getting into medical research. Coming from another engineer who did 2 yrs of post-doc in cancer epigenetics.

Thank you Dr. Scher for having both Dave Feldman and Dr. Matt Budoff together to give us this update about the study. As someone who has been eating low-carb for many years and with an LDL above 300 for the past few years (all my other "numbers" look good), I'm very interested in the results.

My fractionated Lipid results from the Mayo Clinic say I most likely have FH. High LDL 260, low triglycerides 115 (down 60), 40 HDL(up 3). I won't take statins. Research proves nothing positive about statins. Two of my doctor admit 'they don't know how to read the test results'! Jeez. 've been on Keto for 13 months. Lost 80lbs! Feel like a million bucks! Don't feel like I should worry or do anything. Feeling 99% better than last year.

Thank you, Bret! I've been ordering my own lab work annually for 4 years now, instead of having a doctor do it. Thanks to YOU and Dave, I ordered lab work last week from Own Your Labs. It was significantly less expensive than the site I used to order through, and that is BEFORE the 10% Citizen Scientist discount. In the interview, Dave mentions that a lot of low carbers don't have previous blood work to compare to before their dietary intervention. I think I have been getting annual blood work since 2010. I always had low HDL (31-35) and high Trigs (around 200). I thought I was doomed. I was put on blood pressure medication at the age of 38 and met the criteria for Metabolic Syndrome. As an experiment, in 2015, I drank bulletproof coffee every day for three months before getting my annual blood draw. I thought it might be a disaster but just wanted to know. It WASN"T!!! I've been keto or low carb ever since with no plans to go back. Last week my HDL was 76, the highest ever. Trigs were 69, the lowest ever. I also did a fasting insulin for the first time with an HbA1c so I could use that "QUICKI" calculator for insulin resistance measuring. Both tests were only 20 bucks! My LDL is 129 (and TC is 217) so of course I devour as much as I can learn about it as a stand alone marker. I like being a guy that weighs 180 instead of 220 (lbs!) for seven years now. People even say I look younger. I'm 59 but people usually assume 45. The LDL and total cholesterol are the only questionable outcomes in my N of 1 experiments. I will stay tuned to this space and thanks again for your work.

You might want to talk to me. I’m 72 and been low carb since Atkins in the 70s. Never smoked, never fat, no hypertension, no diabetes. Not on any meds. Overall cholesterol…263 Trig..59 Hdl..100 LDL..151 Ratio 3 I’ve been pretty much these numbers forever. Hope this helps.

Dave Feldman is becoming a medical legend! Here is someone challenging the so called forbidden boundaries of Science.

I have been waiting for the results ever since the study was announced! Great stuff overall

I admire Dave for his Love of science in medical , it takes courage

I love Dave's work. I've been doing low carb for about 3 years. I'm not as lean and my cholesterol is not as high as a lmhr. That said, my cholesterol is well over what they consider high, yet all of my markers of inflammation are low and I have a coronary calcium score of zero.

Great interview’s as well as much needed information. I’ve transitioned from Keto to Carnivore 1 month ago and turbocharged my health it feels

Wish I could have been in this study. I have some near LMHS qualifying factors, but had no non-statin bloodwork from before starting Keto in mid-2019 and stopping statins. (I assume that since I was on a statin that my previous LDL was high) My BMI is now about 19.4 for past few years, and average LDL on Keto has been 230+ (over 17 tests). All other bloodwork is great and am athletic. After 1 year on Keto and no statin I had a CAC scan in mid 2020 at age 69 which was 3.78. I intend to get another CAC scan soon which will be close to 2.5 years after the 2020 test. Am very interested to see what it is now. Can't afford the more expensive soft plaque scan. Another interesting side note is A1C and the apparent gradual disconnect for a number of low carb people between low avg blood sugar numbers versus higher A1C. My A1C went from 4.9 initially on keto to increasing up to 5.6 which from my frequent glucose testing is maybe 20pts different. Healthy red blood cells living much longer than avg? I'd be very curious how frequent this observation is among the LMHS population. I found a thread on Dave's website discussing this from a few years ago. I have a pdf of 30 statin RCT's where nearly every one shows virtually no benefit to all cause mortality.

Found this video after I got my lab results back today. 56 yrs old, 5'7" and 132 lbs. I have been doing keto for 3 months and carnivore the last month of the three. My LDL went from 94 in 2020 to 234 today. Hdl 101, and triglycerides 49 My appointment is in 2 weeks. I'm not looking forward to it! I did keto in 2018 and my levels were ideal. I'm thinking I may need some nuts or some other plant products back in my diet. My problem is I get horrible bloating, cramps, and have a lot of undigested food and fat in my stool when I eat vegetables, especially raw ones. Grains are the worst for me, so I won't eat them. On the carnivore diet all my digestive issues went away and being keto adapted my migraines and elbow pain went away too. I'm not going to worry about it yet. Maybe I'll reintroduce small portions of well cooked vegetables like zucchini or cauliflower or some blueberries back into my diet and see how I do.

Very interesting work. Look forward to the final data and conclusions.

Dave I have been so happy with your dedication! Your hypothesis is so interesting. I am low carb but not keto. My triglycerides have gone way down and my HDL is way up. My LDL stays relatively consistent between 120-186 when off statins. They make me feel so badly but I can get my LDL down to 106 before a test just taking the statins twice a week for about a week prior. I stopped smoking ten years ago and have a history of bone density issues and this has also improved on low carb. I wish I could be in your study but since the LDL has stayed consistent I don’t think I qualify. Keep up the great work!

Thank you for adding to our knowledge.

Thanks for all you do Dave. It would also be great if the results of the study could shed some light on AVSCD risk for metabolically healthy "standard hyper responders".