The Anatomy of Pain

I can’t believe this education is just offered for free on YouTube. Thank you so much! I work in a neurology lab and I do a lot of work with neurodegenerative diseases but I don’t often stop to think about the amount of pain patients with these diseases must be in. I work with mice doing gene therapy and I’ve had to dissect and freeze different brain structures and nerves from them. This was so great to watch!

anyone else concerned about the fact he is not just holding a brain in his hands, but the literal casing of a persons consciousness. think of how many memories that were stored there, their first kiss to their last breath. science is truly amazing.

"Those who don't know what pain is, will never understand the true peace!" - probably Pain himself

I'm an RN of 26 years. I'm learning so much! I hope any medical student or professional will take advantage of your amazing videos! Wish I had something like this back in my college days! Thank you guys!

The most amazing stuff about this channel is both of you guys talk about body anatomies with excitement and sheer joy. Happy to see people loving their job and sharing it out to the world. Have a nice day bros

"Let's learn about pain. It'll be fun." Aw crap, he's a football coach.

The fact that this guy has easy access to human body parts is a little unnerving. (pun unintended)

as a med student I feel so glad to be able to have this kind of information as easy as it is here. You guys are great!

My wife is an amputee and has the "phantom pain" in her right leg that does not exist. It is pretty interesting. Thanks for another great video.

"Who would have ever thought that neuroscience and neurology would be complicated?" Possibly the most "meta" statement ever in this series of excellent videos.

Wife on husbands account here: When you started talking about “pain being in your head” and “pain is subjective” I felt that. I’ve given birth now 3 times in the last 4 years. My 1st birth was so painful (birth center so no medications). During my 2nd pregnancy I focused on reframing what sensations I associate with pain, and I would say my 2nd birth (home birth) was my most painless and quickest. It hurt and was uncomfortable, but not painful.

I’ve had chronic pain for many years. This is the first I’m learning of the actual processes of the brain when these signals are firing off or triggered. Thank you.

Videos like this are very helpful, please keep em coming. My daughter has a very rare neurodegenerative disease that required an Ommaya reservoir port, it was implanted down into her third ventricle so she could get a specialized medicine into her csf. This was great for visualizing what that looks like. Her disease also causes her to not feel pain as intensely as a normal person would. But that only seems to be the case from things like scaping her knee or getting poked, hitting her head, etc. She still feels pain from headaches, gastrointestinal, muscle aches and basically anything internal.

This was so interesting. I have fibromyalgia, which is a neurological chronic pain condition, I was recently diagnoses with non-allergic rhinitis and the ENT who diagnosed it was like "yeah, it is really common in people with fibromyalgia." I had never heard of it before and hopped onto my university library and there were so many peer reviewed journal articles about it, something like 70% of people with fibromyalgia report having chronic non-allergic rhinitis. Turns out my brain is convinced that there is something wrong with my sinuses when there isn't, so it sends extra mucus to deal with the non-existent problem. My brain is such a drama queen.

As a healthcare professional and instructor I believe this channel does the public a great service. So many of us know so little about our bodies that it really is shameful. Thank you for your continued work.

I have Paget’s disease of the bone since my teens, a meningioma tumor removed off of T-7 back when I was 30, multiple surgeries & joint replacements, and one hell of a fibromyalgia case. And I can say, fibro, or the chronic never ending pain 24/7 is the absolute worst. I never get a break at all. And I’ve tried everything I can. Right now I’m seeing a chronic pain specialist. She has me on norco & flexeril. They work better than anything else I’ve tried, but tnx to the current opioid BS, I’m not allowed enough norco to actually get me up & functioning like I was hoping for. Anybody else dealing w/ similar issues? And pls, if any Dr’s or govt officials actually read comments, pls pls consider the actual patient and NOT drug addicts when prescribing treatments for their condition. Being denied proper medical care based on this whole opioid “crisis” is a load of crap

If we could not feel pain we would all be dead more than likely, pain saves lives lol.

I really love how he looks so excited about teaching us how amazing all this is. And it really is! Appreciate this video so much. ♡

I had a traumatic spinal cord injury at the age of 21 following an off road motorcycle accident.I fell over 70 feet and it took two hours of yelling for help. I committed the first rule of off road motorcycling:"never ride alone in the woods." Rehab went well and I started my new life in a wheelchair. For the first 20 years all was good except for inconsistent burning (phantom pain) in my legs from my incomplete injury. At 22 years post injury the pain ramped up significantly. Started having burning all across my torso and legs. Doctor finally ordered an MRI of my Cervical and Thoracic spine. Seems that the surgeon on the night I got hurt who operated on me did a shoddy job. At the age of 42 I was diagnosed with Syringomyelia. My spinal fluid was leaking at T-12, L-1 and the fluid was hyper exciting my sensory neurons(burning pain throughout my torso and legs) and killing my motor neurons. Following my first laminectomy I lost all muscle function below my waist and it ramped up my sense of pain. I could not tolerate any breezes or Air Conditioning from vents that touched the hairs on my arms and chest where it triggered off goose bumps the size of blueberries. I underwent four surgeries(Laminectomies.) The first three failed and the third provided relief for two years. I was able to go back to work during that time but then I started having balance and hearing problems on my left side. Turned out I had a large, benign brain tumor that was growing rapidly and crushing other parts of my brain(thalamus.) Following radiation to kill the tumor it triggered Central Pain Syndrome. After living a very active life as a world class wheelchair athlete and then as a coach at the Olympics and Paralympics. I would not wish this kind of constant burning and tremors on anyone(other than Donald Trump who needs to be humbled.) My life since radiation has left me confined at home where my entire life is geared towards avoiding any kind of breeze or noxious stimulation. I remain a coach internationally but at a very reduced level coaching online. Thank you for this insightful talk. Your talk brought back memories of when I got a crash course on neurophysiology, pain and the constant burning that comes with Central Pain Syndrome and Syringomyelia. All the best to you in 2023 and thank you for such an easy to understand anatomy and physiology presentation. Be safe.

I have chronic migraines and there are days where I wish I couldn’t feel pain only because I’m in so much pain that I can’t move or it’ll make it worse. But most of the time I’m ok with pain (as long as it’s not migraine related). I currently have a bad headache as I’m writing this. It was cool to see what happens in your body when you experience pain, and it was super interesting. I didn’t know most of this information, except for the absolute basic stuff like the pain signal sending to your brain then you feel it, but I didn’t know the whole process of how that happens. I would love to see a video on chronic pain, because it is different than just regular pain…at least I think it is.