Autophagy and Neurodegeneration: Autophagy-lysosome Pathway in Neurodegenerative Disease

NovusBiologicals
NovusBiologicals
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Published 2018-11-30
Dr. David Rubinsztein discusses the basic biology of autophagy and its role in neurodegeneration as well as how certain genetic variants in neurodegenerative diseases are associated with compromised autophagy. Original Air Date: November 20, 2018. Learn more about autophagy at www.novusbio.com/research-areas/autophagy
All Comments (11)
  • @CryoEMQueen
    Dude some people are so good at presenting. This should be a skill that is much higher priority in graduate schools than it currently is. Props to Dr. R here
  • @pirasa5
    WOW. What a wonderful talk.
  • @domagojbarac
    this is dr. rubinsztein's masterpiece. can you just say if there might be way to apply autophagy in ALS? misfolded proteins should be "eaten", along with excess of glutamate (neurotransmitter). also, is there a connection between mentioned glutamine (acid) and glutamate in enormous quantities in ALS?
  • @bobcocampo
    Any research on autophagy and retinopathy and CKD?
  • @ramesh123443
    Dr. Rubinsztein talk is very interesting. Does mitophagy proteins have any role in Huntington's disease for PolQ expansions clearance? However, it is NOVUS responsibility to take the care about the sub-titles of the video and made a lot of big mistakes about terminology spellings. Please fix for large viewership across the globe or remove the subtitles to avoid the confusion.
  • @toby2524
    My father has Parkinsons, dementia and had skin/lung cancer. I am 20 years old with no signs of anything but what tests can I take to see my genetic chances of getting such issues? I'm British so would I just ask my GP for advice ect? Great video just heard of autophagy today and was recommended this video
  • @AceKinG2024
    How many days someone should fast to activate autophagy?
  • @zebethnewton9456
    How wonderful is the body! Now I know, the body is not only the temple of GOD but it is more technically sophisticated than anything in the world. Better take care and learn the power if it.