The Importance of Place with neuroscientist Richard Morris (U. of Edinburgh)

Publicado 2024-07-25

HIPPOCAMPUS SPOTLIGHT: A conversation on navigation and memory with Richard Morris, a renowned neuroscientist famous for his groundbreaking work on memory and the development of the famous Morris Water Maze. Andrea's research into the early years of hippocampus/navigation research illuminates Morris's early career and interactions with notable scientists like John O'Keefe and Lynn Nadel, touching on previous discussions about The Hippocampus as a Cognitive Map and topics including place cells, longterm potentiation, and the hippocampal role in spatial memory and learning. Discover the fascinating trajectory of Morris's career from Sussex University to St. Andrews, and his contributions towards various aspects of memory, research including Alzheimer's research. Learn how modern techniques like calcium imaging and optogenetics are pushing the boundaries of our understanding of memory and cognition.

00:00 Introduction and Greetings
00:06 Early Academic Journey and Influences
01:04 Meeting John O'Keefe and Lynne Nadel
02:10 Developing Interest in Place Cells
03:43 The Concept of Place and Memory
05:34 Personal Anecdotes on Place
10:03 Transition to St. Andrews and Career Shift
13:34 The Birth of the Morris Water Maze
16:18 Impact and Recognition of the Morris Water Maze
22:51 Exploring Long-Term Potentiation
29:41 Collaborations and Further Research
31:45 The Importance of Face-to-Face Meetings
32:42 The Journey of a Young Couple in Neuroscience
34:19 Discovering Grid Cells and Winning the Nobel Prize
35:51 The Role of Place Cells in Navigation and Memory
44:23 Advancements in Recording Techniques
49:29 Exploring Rat Cognition and Memory
56:07 Translational Work and Alzheimer's Research
59:15 Concluding Thoughts and Future Directions

#navigation #hippocampus #neuroscience #memory #richardmorris #andreahiott #loveandphilosophy

Developments of a water-maze procedure for studying spatial learning in the rat: www.sciencedirect.com/science/article/abs/pii/0165…

Neuronal signature of spatial decision-making during navigation by freely moving rats by using calcium imaging: www.pnas.org/doi/full/10.1073/pnas.2212152119

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Encouraging results for Alzheimers vaccine: www.nature.com/articles/news001221-10

Richard Morris Google Scholar: scholar.google.com/citations?user=LGBPqBQAAAAJ&hl=…

Morris water maze: www.ncbi.nlm.nih.gov/pmc/articles/PMC2895266/

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