Ergothioneine: A 'Longevity Vitamin' With Potential Benefits For Age-Related Outcomes?
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Published 2021-04-18
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Papers referenced in the video:
Dietary Thiols: A Potential Supporting Strategy against Oxidative Stress in Heart Failure and Muscular Damage during Sports Activity:
www.ncbi.nlm.nih.gov/pmc/articles/PMC7765667/
Ergothioneine levels in an elderly population decrease with age and incidence of cognitive decline; a risk factor for neurodegeneration?
pubmed.ncbi.nlm.nih.gov/27444382/
Is ergothioneine a ‘longevity vitamin’ limited in the American diet?
www.ncbi.nlm.nih.gov/pmc/articles/PMC7681161/
Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility:
pubmed.ncbi.nlm.nih.gov/32295884/
Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease:
pubmed.ncbi.nlm.nih.gov/31672783/
Ergothioneine – a diet‐derived antioxidant with therapeutic potential:
febs.onlinelibrary.wiley.com/doi/full/10.1002/1873…
Ergothioneine, a metabolite of the gut bacterium Lactobacillus reuteri, protects against stress-induced sleep disturbances:
www.nature.com/articles/s41398-020-0855-1
Distinct actions of the fermented beverage kefir on host behaviour, immunity and microbiome gut-brain modules in the mouse:
microbiomejournal.biomedcentral.com/articles/10.11…
All Comments (21)
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You are quickly becoming my favorite YouTuber. Relevant, important information. Asking the logical questions and walking us through the studies and data to answer them as best as we can. Real actions we can take on the new information. It's amazing this is all free. Thank you so much.
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Warning about L. reuteri - it increases oxytocin. Oxytocin is often touted as a panacea, the 'love hormone', but it can increase pain in women with chronic pain conditions and was found to increase anxiety-like behaviors in females in a rodent model. My own experience with an L reuteri probiotic (the Lifeway digestion shot) is that it caused labor pain-level menstrual cramps; I almost went to urgent care.
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Thank you for another outstanding educational video. The world is a better place because of humble and kind people such as yourself! Please keep up your excellent work and may God richly bless you.
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Am currently finishing up my dissertation on EGT, and you're spot on with this. This is a good primer for EGT!
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Another terrific, understandable video. I am really learning a lot from you. BTW, I was led to your channel by your excellent interview with Richard at Modern Healthspan (another channel that does a good job of summarizing the research in the health and longevity field). Thank you!
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great video. Thank you! You mention sulforaphane which the "found my fitness" doctor talked about, but few others have talked much about. Would be great to see a video on sulforaphane, because it seems to have a particularly good effect preventing prostate cancer. Good news for us men.
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Porcini! One my favorites to buy dry and reconstitute.
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this channel is so unrated. amazing content, I am making my own kefir...
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Good to hear
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I have been eating cooked button mushrooms (usually white) almost daily for a couple of years. With all of the diet and exercise interventions I do, I was hoping to feel like superman by now . It has not happened.
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Excellent information, thank you.
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L Reuteri ATCC6475 has shown great anti-ageing effects in mice, but I've no idea if it releases ergothionine. There's a long thread about 6475 on Longecity forum. It cultures well in milk, yielding a pleasant tasting yoghurt.
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Interesting. I do eat mushrooms but not kefir. Well, we’ll see what the next update shows. Thanks!
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Another great Yt .. thank you
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This channel is the best.
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Excellent. It draws me to consume more Mushroom and Miso soup, luckily since that's a favourite of mine.
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Nice work! Are you using google presentation or another one? I like how fast and well-presentated is the layout. easy and effective!
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This is simply brilliant! Thank you very much and please bring us many more of these. Much appreciated...
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😊I can tell you love what you do! You present this research so effortlessly. Thanks for sharing 🍉🥑🍇New subscriber
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Excellent ! Thank you !
