Which Nutrients Are Associated With A Younger Brain Age?
Published 2024-07-10
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Paper referenced in the video:
Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study www.nature.com/articles/s41514-024-00150-8
All Comments (21)
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I wonder if astaxanthin could replace lutein and zeaxanthin... Very enlightening video, thank you Michael! I guess it wasn't a bad idea to add peanut butter to my diet..
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The single food high in most of those nutrients is...egg yolks! High in EPA, Vit E, choline, lutein, zeaxanthin. Also remember the more orange the yolk, the higher the lutein content. Most crappy mass produced eggs has light yellow yolks, low in lutein. You want dark orange, high in lutein. Egg yolks are literally a super food.
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Hey Michael 👋 I wonder, considering all this, what would be the ideal amounts of Walnuts, Almonds, Peanuts and Pistachios ? I already eat them regularly but it's completely at random, a handful here, a handful there... It'd be nice to have an idea of an optimized amount for each. Knowing this, I'd probably start preparing a bunch of those optmized nuts snack in advance. Convenience is king to keep these efforts going after all. Thanks again for all you do !
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Yet another informative video of excellent quality . Thanks for your work
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Fasting, intermittent or periodic, is also a powerful, and inexpensive, mean to fight brain aging , as it translates into significant production of BDNFs which are actually fertilizers for the brain.
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It would be cool to combine your diet measurements with standardized brain function measurements. Maybe with something like braingauge from corticolmetrics or the brain games on e.g. brainhq.
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I think this topic is very interesting, and you're doing great work. But I have to point out that comparing the simple average of the various nutrient markers between 2023 and 2024 isn't particularly useful, especially since octedeconic acid and choline values are a 1 to 2 orders of magnitude larger than the others. You should take a weighted average if you wish to make comparisons between these collectively.
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Good to know.
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There is mounting evidence that just like the gut microbiome determines physical health there is a brain microbiome that determines brain health. Your markers are just that not determinants since correlations like this do not prove causation. There is stronger evidence that insulin resistance, mitochondrial function and degree of senescence are the key factors as in other cells.
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Great in-depth analysis, as usual! Among fatty acids, pentadecanoic acid (C15:0) is quite hyped lately due to its potential anti-ferroptotic effects, and some even suggest it should be classified as an essential fatty acid. Might be interesting to see how it affects brain function. Maybe iollo will consider adding C15:0 in its panel. Any news regarding the addition of ergothioneine in iollo's panel? Have you received the results from them?
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thanks for the video. a bit confused about the 5 first checkmarked nutrients, where do you get them, or are they produced in the body? I know EPA and Choline are found in supplements and food
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Bacon fat has a lot of eicosadine acid (0.44 mg). Do I understand you correctly that this could imply that bacon fat (in moderation) could possibly be part of a good longevity diet?
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What food sources do you use to get choline? I know egg yolks are a very good source, but due to my APOE4 gene I need to limit my intake.
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what you think about creatine now for blood vessel? is good?
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so what ur saying is I should drink some eggs?
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Which Nutrients Are Associated With A Younger Brain Age? Captain Crunch, Count Chocula, and jello!
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Hmm makes case for keeping in eggs and fish or fish oils
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1) Good summary, thanks. 2) Re: Lutein and zeaxanthan, the most bioavailable source, in my understanding, is egg yolks.
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I don’t take astaxanthim it may be good but it crashed my dht levels so bad I lost my sex drive . Much like finasteride - so I’m sensitive to dht inhibitors
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Err.... Seems that I have to rethink my diet. Fortunately I really like peanuts and pistachios.