Weight Regain after Wegovy or Zepbound: Unveiling the Truth | Dr. Dan | Obesity Expert

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Yes, please do a video about maintaining the weight loss, as best as possible, after stopping the medication.

I am absolutely terrified I’ll gain it all back. I’ve been on one pic for just over a year. I’ve gone very slow in the increases of dosages. I’m still only at .75 and have lost about 37 lbs. but it is very hard work! If I don’t actively have a calorie deficit I don’t lose anything. I’m hoping that my Dr is right about going slow and working hard. I’ve had zero nausea and no diarrhea at all. I get acid reflux, but that was present prior to Ozempic. I currently do intermittent fasting which works well for me. Hoping I can resume my speed walking this spring. I’ve been quite immobile since last July when I broke my tailbone. Wish me luck.

Love your channel! Would love to hear you talk about maintaining weight loss. That would be extremely helpful. Thanks!

Need to have a plan and follow Dr Dan!

If you want to understand more about why the weight regain happens, there is an excellent discussion about "set points" in video "NIH Obesity Research Task Force Symposium: Medications to Treat Obesity: Past, Present, and Future" (Second speaker)

Need to find some way to turn off hunger in the gut lining. My Brain loves not feeling hungry! Cooking is such a waste of time. Hypnosis.? fiber? Hate my gut telling me to eat!

Is there a problem with being on a maintenance dose of Ozempic to maintain my weight loss for the rest of my life? If diabetic patients can take Ozempic for their diabetes, then why can’t I take it for weight loss maintenance? I was prescribed Ozempic because my BMI was 45, I have sleep apnea, high blood pressure and high cholesterol, so I had a lot of co-morbidities. The weight loss I have had as a result of Ozempic has resulted in a 40 pound weight loss (I’m still considered obese so my BMI is still too high and I need to loose more weight). My blood pressure is now normal and my cholesterol is now under control. With my weight loss I’m now exercising daily and find movement much easier due to less pain. I’m 68 and I’ve been yo-yo dieting since I’ve been a teenager; I know how to loose weight, but my hunger has always been an issue - it’s not an emotional thing, but my gut keeps telling my brain that it needs food, the Ozempic takes away all that noise. Now I don’t have those constant cravings for high calorie, sweet and processed foods because the Ozempic takes care of those cravings, I eat a much better and more balanced diet consisting of primarily vegetables, seafood and lean protein. I’m not interested in doing a carnivorous or keto diet as way to restricting for me. Once I’ve lost another 30 or 40 pounds (depends on what my body feels best at), I’d like to know that I can still get Ozempic to maintain that weight loss. I’m so tired of this constant up and down, yo-you dieting. Edited to add that I’ve finished the video and Dr. Dan recommends staying on the drug long-term, which makes me so happy to hear. I really don’t want to gain back the real estate that I’ve lost, I know the mechanics of maintaining weight loss, I’ve just never been able to do it, so history tells me that I won’t be successful if I come off Ozempic.

That’s a really informative video, I would love to see another video specifically talking about dosage. Most of these studies especially with Mounjaro start with at the therapeutic dose (5mg), however many people have remained on the 2.5mg dose (never went up), and have lost a significant amount of weight on that dose, wouldn’t it make sense that these people might be able to maintain their weight better on the long run? Especially that it will be easier for them to kinda space out that dose until slowly getting off of Mounjaro. Probably those who were not able to maintain their weight titrated up to a very high dosage that their body got used to already, so they were not able to properly get their body used to no Mounjaro.

This video is crushing. I’m not diabetic but struggle with hormonal imbalances and hypothyroidism. Despite routine weight lifting, regulating my thyroid, and gastric sleeve, I’ve only lost half the weight. I’m hoping a dr will prescribe Wegovy to lose the last 40 lbs.

Dr Dan, thank you for telling us the facts straight out. I’m curious what the characteristics ( genetic, age, etc.) and habits were at the time of the study whereby the 16% were able to maintain 80% of their weight loss. This would offer some clues and perhaps hope for the rest of us wanting to maintain the healthier result should we be so fortunate. Did they ALL increase their protein and strength training, decrease calories and fats? Would be helpful if the study included that information. Thank you again for an informative video.

This has me slightly terrified for the future now. I have lost over 20% of my weight over 11months on wegovy (1.7mg now) and some more to go @74kg now. I have to redouble my efforts and will be listening out for your future videos. Thanks dr Dan.

My insurance which covers a lot of people, voted to end all weight loss drug coverage starting April 1. I am being seen in a weight loss clinic, so at least will likely have some support to try anything that may be still covered, although nothing really works as well, but at least most of those things are older or at least cheaper. Part of the problem is they can't get the rebate because they said no new prescriptions starting in Oct 2023. From what I understand, and their over-riding interest is that they have not raised premiums for the last 5 years, and plan to never raise them again (which given inflation being what it naturally does means dropping coverage for more and more things every single year). So 25,000 people in my state will be kicked off, most will likely be cold turkey. I have a prescription to lower the dose for the next couple of months so hopefully won't be as steep a cliff. There is push back from physicians as this amounts to "abandonment of care", but I don't see much hope that they will change their minds. Abandonment of care can be considered medical malpractice at least if the doctor does it, apparently insurance companies have no such requirement?

Is there a corresponding lifestyle change program along with Mounjaro to help prevent the drastic weight gain?

Ohh, you explained that so well, thank you!! 🙃💪🏻 I've always been at a normal weight but now gained 30kg within 3 years due to taking Prednison. I hope hope HOPE my Endokrinologist will give me some sort of WeGovy as I keep gaining weight, no matter how hard I try... Maybe I would only have to take it as long as I have to take Cortison. Oh and another side note, I wonder if the participants lost some muscle weight and regained the fat because of a lowered amount of calories burnt by muscle mass? Maybe that regain could be addressed by lifting weights while on the medication? I generally wonder what the people who kept their weight off did differently...

Yes sadly... so disappointing and now I can't get it anymore

It seems to me that these medications don't directly cause the burning of fat or things that would directly cause weight loss. It seems that it affects things like appetite & intrusive thoughts of food. So say you've lost 50 lbs on the meds. And then stop. Is the struggle to keep that weight off going to be much different from the struggle to keep 50 lbs off, lost in the unmedicated way? To me, who has lost (and gained) lots of weight over the course of my 62 years, there's a white-knuckle daily struggle to keep a large weight loss off - is that struggle different for post-medication people? Just, physically different?

Doctor I just finished 2nd week of mounjaro 2.5 and I noticed mid if the second week I'm getting intrusive depressive thoughts it's b4 my period but I dont usually feel this bad then I stared having bolts of crying which I dont usually have either ended up with two major panic attacks and a major depressive episode with a sprinkle of paranoia...is this something u heard about this medication doing to some ppl..my periods I get mood swings a lil emotional this was on ster😢it scared me

So definitely we need take the medication for ever 😢?

Well.. my last program was smoking cigs… I quit in 2019 and gained all this weight. It’s so annoying, but I refuse to go back. 36 years old, went from 160 to 250 in two years