Gastrulation | Formation of Germ Layers | Ectoderm, Mesoderm and Endoderm

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Published 2018-07-20

Lesson on Gastrulation and the Formation of the 3 Germ Layers known as the Ectoderm, Mesoderm and Endoderm. Gastrulation is a process whereby a bilaminar disc (comprising the epiblast and hypoblast cells) gets transformed into a trilaminar disc (comprising the germ layers of ectoderm, mesoderm, and endoderm). Gastrulation is responsible for forming the 3 germ layers including the ectoderm, mesoderm and endoderm.

After the egg is fertilized by a sperm, the resulting zygote will eventually develop into a blastocyst, which contains an inner cell mass that will become the embryo. The outer cells on the blastocyst are known as trophoblasts, which differentiate into syncytial trophoblasts and cytotrophoblasts. The syncytial trophoblasts will invade the endometrium of the uterus and implant the blastocyst. The blastocyst will eventually become embedded into the endometrium. The inner cell mass of the blastocyst will differentiate into epiblast and hypoblast cells, forming the bilaminar disc. The process of gastrulation transforms this bilaminar disc into a trilaminar disc comprised of the 3 germ layers.

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JJ

***EXCLAIMER: The content (ex. images) used in this lesson are used in accordance with Fair Use laws and are intended for educational/teaching purposes only.***

NOTE: Although I try to be 100% accurate, if you see any mistakes in this video, please let me know and I will make a correction. Thanks so much!

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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

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Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.

@lorijosephson9062 5 years ago

Second! I love these videos they help me so much I’m twelve and I’m gonna be a cardio thoracic surgeon

@clarachimiti7239 8 months ago

Thank you for the amazing video! Cheerings from Brazil!

@saravanakumar3034 3 years ago

Your explanation and visuals are amazing..now i have cleared about the germ layer formation.. this way surely will make to love embryology... Thank you so much sir

@alysekasethiran8640 1 year ago

Excellent explanation. You go very thorough in details. Thank you so much.

@alexander22600 3 years ago

That was awesome. Amazing visuals and explanation

@renan8387 4 years ago

thank you for the explanations! i really appreciate this! this helps me a loooot!❤️

@mathew555s 3 years ago

Extremely helpful video. This served as a great foundation to embryology.

@bitchoflivingblah 3 years ago

Endoderm does not entirely form from the hypoblast, it is derived from mesendoderm an intermediate tissue that has the potential to differentiate into mesoderm or endoderm depending on inductive signals it receives. You can find some hypoblast (visceral endodoerm) cells in the definitive endoderm but most of these cells are derived from the ingress of epiblast cells.