Coffee with EMBL #16: DeepMind and the Future of AI in Life Sciences (Part 1)
373
2024-07-03に共有
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Guest speakers:
🎙️ Dame Janet Thornton, Director Emeritus (2001-2015), Group leader and Senior Scientist, EMBL-EBI, 1994-2023
Dame Commander of the Order of the British Empire (2000)
Joint Vice President of ERC, 2019-2020
🎙️ Sameer Velankar, Team Leader and Senior Scientist at EMBL-EBI since 2000
🎙️ Chris Sander, Professor in Residence of Cell Biology, Harvard Medical School
Group Leader and Senior Scientist, EMBL Heidelberg, 1986-1998
🎙️ Andrew Miller, First Head of EMBL Grenoble, Group leader, 1975-1980
🎙️ Anna Kreshuk, Group leader at EMBL Heidelberg since 2018
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Timestamps:
0:05 - AI's Impact on Protein Folding with EMBL and DeepMind Experts
Angus Lamond welcomes attendees and begins the discussion on AI's impact on research and society.
6:25 - Predicting Protein Folding Using AI
Thomas Vaccari explains protein folding and the role of amino acids, highlighting an AI-based method for accurate predictions.
12:07 - AI-Predicted Protein Structures and Their Accessibility for Research
Samia Velankar discusses the AlphaFold database, its extensive protein structure predictions, and its open accessibility.
17:55 - DeepMind's AI-Powered Protein Structure Prediction and Its Impact
Discussion on making AI research openly accessible and the projected growth of the AlphaFold database.
24:03 - AI-Driven Protein Structure Prediction and Its Limitations
Janet Thornton and Chris Sander discuss the limitations and accuracy issues of AI models in protein structure prediction.
32:42 - Protein Structure Prediction Using AlphaFold and RosettaFold
Chris Sander highlights the caveats of AI predictions, including the limitations in drug design potential.
42:09 - AI in Structural Biology, Including Database and Machine Learning
Angus Lamond and Chris Sander discuss the importance of databases and community contributions in AI-driven structural biology.
47:55 - The Future of Structural Biology Infrastructure and Technology Investment
Andrew Miller emphasizes the importance of investing in structural biology infrastructure, like cryo-EM and synchrotrons.
54:56 - Applying AI to Image Analysis in Biology
Anna Kresha explores AI applications in imaging research and the potential for AI in segmentation, tracking, and behavior analysis.
59:54 - Using AI to Analyze Biological Data and Predict Cellular Interactions
Discussion on building predictive models of cell biology through AI and machine learning.
1:05:56 - AI's Role in Structural Biology, Limitations, and Future Prospects
Discussion on the necessity of human validation for AI predictions and the experimental validation needed for structural biology.
1:10:47 - AI's Potential in Protein Structure Design and Material Development
Chris Sander discusses AI-assisted protein design and its implications for biotherapeutics and material science.
1:15:07 - Predicting Protein Structures and Ligand Interactions Using AI
Challenges of predicting small molecule ligand interactions and the competitive dynamics affecting protein structure prediction.
1:19:52 - AI Applications in Biology: Protein Folding, Health Data Analysis, and Imaging
Discussion on AI's potential in health data analysis, disease prediction, and image annotation in microscopy.
1:24:03 - Using AI in Biology: Cancer Research and Data Sharing
Chris Sander highlights the challenges and potential of AI in clinical research, emphasizing the need for well-organized databases.
1:29:30 - AI Applications in Protein Folding, Image Analysis, and Clinical Research
Angus Lamond and Thomas Vaccari discuss AI's broad impact on society and thank contributors for their insights.
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Coffee with EMBL is hosted by EMBL and moderated by EMBL alumnus Angus Lamond, Professor of Biochemistry, University of Dundee | Former Group Leader at EMBL Heidelberg, 1987-1995, who co-organises the series together with Thomas Vaccari, Associate Professor, University of Milan | Former Predoctoral Fellow (Ephrussi Group) at EMBL Heidelberg, 1999-2004) and the EMBL Alumni Relations team.
Learn more about the series at www.embl.org/about/info/alumni/coffee-with-embl/
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Access live chat highlights (+ useful links and notes) at oc.embl.de/index.php/s/yIJ0oxrGTtuGFeM
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Recorded on Friday, 17 September