Stroke and death after Moderna

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Published 2024-05-16
Fatal Post COVID mRNA-Vaccine Associated Cerebral Ischemia

pubmed.ncbi.nlm.nih.gov/37064937/

Keywords: COVID-19; Moderna vaccine; cerebral edema; neurology; stroke.

McMillan N, Rosenberg HJ, Anderson MP, Pal P, Stephenson K, Fehnel CR. Fatal Post COVID mRNA-Vaccine Associated Cerebral Ischemia. Neurohospitalist. 2023 Apr;13(2):156-158. doi: 10.1177/19418744221136898. Epub 2022 Dec 5. PMID: 37064937; PMCID: PMC10091442.

Department of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Background

Venous thromboses have been linked to several COVID-19 vaccines

Here we describe a case of post-Moderna COVID-19 vaccination arterial infarct,

with vaccine-associated diffuse cortical edema,

that was complicated by refractory intracranial hypertension.

Case summary

24 hrs after receiving her first dose of the Moderna COVID-19 vaccine,

a 30-year-old female developed severe headache.

Three weeks later she was admitted with subacute headache and confusion.

Imaging initially showed scattered cortical thrombosis with an elevated opening pressure on lumbar puncture.

An external ventricular drain was placed,

but she continued to have elevated intracranial pressure.

Ultimately, she required a hemicraniectomy,
but intractable cerebral edema resulted in her death.

Pathology was consistent with thrombosis and associated inflammatory response.

Conclusion

Though correlational, her medical team surmised that the mRNA vaccine may have contributed to this presentation.

The side effects of COVID-19 infection and vaccination are still incompletely understood.

Though complications are rare, clinicians should be aware of presentations like this one.

More information

Had prior asymptomatic COVID-19 infection three months earlier

24-hours after first dose of the mRNA COVID-19 vaccine (Moderna).

Developed severe, atypical throbbing bi-frontal headache

Headaches were atypical

(no prior headaches)

Three weeks after vaccination

Developed blurred vision and confusion

Bifrontal headache with photophobia

Lumbar puncture revealed lymphocytosis

Broad spectrum antimicrobial coverage was started.

Her mental status acutely worsened later that evening

New left hemiparesis.

Elevated D-dimer

CSF cultures and PCR testing returned negative

Intracranial pressure remained refractory to maximal medical management,

including deep sedation, paralysis and hypothermia,

prompting a right decompressive hemicraniectomy.

The patient expired from refractory cerebral edema.

Brain autopsy showed infiltrates of CD8 and CD4-positive T-cells,

in association with intravascular thrombi

Fungal and bacterial stains were negative.

Discussion

Diffuse endothelial damage and vessel wall inflammation,

suggested an underlying pro-thrombotic state and T cell inflammatory response.

The arterial infarct in this case is likely related to a pro-thrombotic state

Due to the large volume of infarction, the patient was not started on anticoagulation after extensive discussion of the risks vs potential benefit.

In summary, administration of COVID-19 vaccine was considered a possible cause of the extensive multifocal arterial thromboses with associated inflammatory response and elevated intracranial pressure given the temporal association.

The mechanism for initial elevation in intracranial pressure is not known but may relate to cerebral autoregulatory changes in the setting of cortical microvascular thrombosis.

petermcculloughmd.substack.com/p/fatal-post-covid-…

Suspected Unexpected Serious Adverse Reaction (SUSAR) such as this would have put a pause on the entire study and an investigation into why this happened and a call for risk mitigation measures to prevent the same complication from happening to more subjects.

All Comments (21)
  • @ret4350
    Fauci, Bill Gates. WHO, all need to be held accountable.
  • @daveb8449
    A lot of people need to be in prison over this scam.
  • @ZENIGMATV
    I haven’t trusted the government for years but now I despise it.
  • @KittyBootie
    When I was asked by my gynecologist if I had taken the Covid jab, I said I didn’t think it would be a good idea based on my having Factor-5 clotting disorder. She proceeded to tell me my chance of a blood clot was much greater if I caught Covid. I said no thanks and haven’t been back to her in 3 years. I’m done with doctors unless I break a bone.
  • The American people would like to thank Dr. John Campbell for his service. We are forever grateful.
  • @yucafries7681
    The millions of doctors who violated their patient’s right to informed consent should immediately quit. We don’t need liars to poison us
  • The great awakening is when the world realizes that we are ruled by an evil cabal
  • @jpguthrie6669
    I moved to Japan some years ago, and was here during the pandemic. As an American, I had assumed the people in Japan had fewer rights than what I was used to, and fewer rights than those enjoyed in Europe. The pandemic proved that wrong. The first thing I noticed about Japan's response to the pandemic was the lack thereof. There were essentially no mandates whatsoever, the only real restriction being that against incoming international travelers. Japan did not mandate business or school closures, Japan did not mandate staying at home, Japan did not mandate restrictions against domestic travel, Japan did not mandate restrictions on indoor dining. Japan did not mandate masks or vaccines. Japan's high court some years ago ruled that childhood vaccine requirements were unconstitutional, and that children could not be denied entry to school for not being vaccinated. This ruling also applied to adults and employers. Japan's pandemic response was entirely voluntary. And it was surreal during that time to live in a place where I could live normally, that is, go out and work, shop, and do whatever in a normal manner, when people in other places around the world were locked down, quarantined, forced to get vaccinations or lose their jobs, etc. For those who would like to live in a place where the state is kept out of people's hair, Japan is a great place.
  • @tooletime09
    My sister was 39 years old and days after she took her first jab she complained of headache and neck pain. A few weeks went by and she took the second jab, 2 days after she had a massive stroke in the shower. 39 years old healthy mother of two. She fought so hard for her life but after brain surgery it was just too much and she passed away. Rip Jennifer, I love you forever. For those of you that have similar things happen to your family just know that you are not alone.
  • @hipnicity
    I am SO GRATEFUL that I said “no” to big pharma!
  • Without full disclosure they forced people to participate in a clinical trial without their consent. That's horrific.
  • @DavidPriller
    Both of my parents bought into it and took it. They both passed away three weeks from each other a year later, heart attack and stroke. I didn’t take it and they shunned me for it. Rip mom & dad
  • @roberttodd5338
    You finally said it John! "A Ban on ALL vaccines." I agree.
  • @dannyhendy
    How it started: Safe and effective How it's going: Heart attacks and strokes in children have always been normal.
  • @lynnedavis4819
    A lot of people feel that these demons should be held accountable . But when is it going to happen.
  • @pollygraff4940
    Exactly how the killed my husband. A massive stroke. The hospital refused to treat him or place him into intensive care, he was dumped in a side room covered in his own waste and died two days later. I’m my eyes he was murdered.😢😢😢😢😢😡😡