How Gut Bacteria Diversity Improves Health

When a medical doctor connects the dots, there’s hope. Sir, you’re on the right track to crack the mystery of keeping healthy.

One of the best ways to balance your gut is to do some extended fasting to get rid of the gut bacteria that unbalance the gut. These usually overgrow because you eat a lot of simple carbs that allows them to go wild and outgrow the more beneficial ones, that usually require more nutrients than just sugar to grow and grow slower. Many of these guys feed on the other guys and that is the benefit, like l reuteri. Some of the many benefits of doing occasional extended fasting: Blood clotting is reduced and blood clots and arterial plaque are reabsorbed into the body. High blood pressure is lowered to normal levels very quickly while fasting. Fribrosis/scarring is reversed over time. Fasting increases nitric oxide release. Telomeres are lengthend and fasting also increases anti-aging Yamanaka factors. Fasting stimulates phagocytosis, the ingestion of bacteria, plaques and viruses by the immune system. It will also remove any 'foreign material' that is not supposed to be there. Reflexes and short term memory are increased. Fasts from 36-96 h actually INCREASE metabolic rate due to norepinephrine release! After 72 hours or more fasted, your body recycles as much as 1/3 of all immune bodies and creates new ones, rejuvenating your entire immune system. Fasting can help with MS, Depression, BPD, Autism and seizures. Thymus is regenerated, which suppresses aging and renews the immune system. The thymus also plays a vital role in fighting cancer. Weight loss from daily caloric restriction has 1/4 to 1/3 of the weight lost as lean tissue while many studies show fat loss from 36 h fasts without losing any lean tissue! The hunger hormone ghrelin also lowers with extended fasting and rises from dieting. Blood sugar and insulin are lowered, allowing white blood cells to move more freely throughout the body and do their job. Ideal blood sugar is around 80. Some viruses activate glycolosis (the release of sugar in the body) and clinically it has been shown that decreasing glucose metabolism in the body weakens the influenza virus. When you move out of MTOR your body shuts down the building blocks of the cell which are used to produce organelles and proteins. This means the mechanisms needed by viruses to replicate are by and large unavailable when you are in a deeply fasted state. What breaks a fast? Anything with protein or carbohydrates in it will break a fast, though if the amount is tiny you will go back into ketosis very quickly. Most teas and herbs are OK. Most supplements and meds will either break ketosis directly or contain a filler that will. Many medications are dangerous to take while fasting so you may have to talk to your dr. about discontinuing them during a fast. Fasts of several days will not affect short term female fertility and may increase long term fertility, especially in women with PCOS. Does fasting lower testosterone? No, it raises it when the fast is broken by increasing lutenizing hormone The hormone Leptin is an immunomodulator that keeps the body from attacking itself and obesity causes leptin resistance. Fasting very quickly reduces leptin resistance and leptin levels and one day of fasting can cut your leptin levels in half and gets your immune system working properly again! Does the body preferentially prefer glucose as a fuel? No, except for brief periods of very intense exercise, your body mainly burns fats in the form of free fatty acids. Your brain also prefers to burn ketones at a rate of around 2.5 to 1 when they are available in equal quantity to glucose. Fasting stimulates the AMPK complex and activates autophagy. Autophagy (literally self eating) will cause cells to recycle foreign matter such as viruses and kill cancerous and senescent cells. AMPK does many helpful things in the body including activating the body's antioxidant defenses. Deep ketosis virtually eliminates chronic inflammation in the body. This can offset the life threatening symptoms of viral pneumonia which effectively kills you through inflammation. This also creates BHB ketones in your body, which help your immune system and anti-oxidative system, especially in the brain. When not in ketosis, the brain can only burn carbohydrate, which produces a great deal of damaging ROS the brain has to deal with. It increases mitochondrial function and repairs mitichondrial DNA, leading to improved ATP production and oxygen efficiency and thereby making cells better able to fight off infection. Increased mitochondrial function also has the added benefit of increasing your metabolism and cancer prevention! When you fast, this stimulates apoptosis in senescent or genetically damaged cells, which destroys them. Senescent cells are responsible for many of the effects of aging and are a root cause of the development of cancer. Fasting also releases BDNF and NGF in the blood which stimulates new nerve and brain cell growth. This can help a great deal with diseases like MS, peripheral neuropathy and Alzheimers. In fact, the biochemical regulator of BDNF production is beta-hydroxybutyrate, which is the same ketone the body produces to nourish the brain while fasting. Fasting also increases telomere length, negating some of the effects of aging at a cellular level. A fasting mimicking diet for 3-5 days in a row also provides many of the same benefits as water fasting. FMD usually has 200-800 calories, under 18 g of protein and extremely low carbs. Exogenous ketones can aid with fasting, making it easier in healthy people and allowing some people with specific issues to fast in spite of them without worrying as much about hypoglycemia. Children, pregnant or nursing women should not fast for periods longer than 16 hours. People with pancreatic tumors or certain forms of hypoglycemia generally cannot fast at all. Type 1 diabetics can also fast but it is more complicated and should be approached with caution as it could lead to ketoacidosis. Those with Addison's disease may also be unable to fast without liberal use of exogenous ketones, depending on severity. If you experience extreme symptoms of some kind, especially dizziness then simply break the fast and seek advice. Resources: https://pubmed.ncbi.nlm.nih.gov/23707514/ https://clinical.diabetesjournals.org/content/36/3/217 https://pubmed.ncbi.nlm.nih.gov/27569118/ http://www.sciencedirect.com/science/article/pii/S0005272806000223 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413655/ https://academic.oup.com/ajcn/article/81/1/69/4607679 https://pubmed.ncbi.nlm.nih.gov/25909219/ https://www.nejm.org/doi/full/10.1056/NEJMoa012908 https://pubmed.ncbi.nlm.nih.gov/15522942/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017674/ https://www.sciencedirect.com/science/article/pii/S1931312809002832 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895342/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526871/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/ https://www.collective-evolution.com/2017/05/16/study-shows-how-fasting-for-3-days-can-regenerate-your-entire-immune-system/ https://www.health.harvard.edu/heart-health/abundance-of-fructose-not-good-for-the-liver-heart https://pubmed.ncbi.nlm.nih.gov/20102774/ https://pubmed.ncbi.nlm.nih.gov/31877297/ https://www.ncbi.nlm.nih.gov/pubmed/23876457 https://repository.upenn.edu/cgi/viewcontent.cgi?article=1537&context=edissertations https://www.cell.com/cell/fulltext/S0092-8674(19)30849-9 https://www.ncbi.nlm.nih.gov/pubmed/25686106 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779438/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407435/ https://www.arcjournals.org/pdfs/ijrsb/v3-i11/7.pdf https://www.amjmedsci.org/article/S0002-9629%2815%2900027-0/fulltext https://pubmed.ncbi.nlm.nih.gov/20921964/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141719/ https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2019.33.1_supplement.819.10 https://www.biorxiv.org/node/93305.full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/ http://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00224-7 https://www.ncbi.nlm.nih.gov/gene/25712 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093158/ https://n.neurology.org/content/88/16_Supplement/P3.090 https://www.nia.nih.gov/news/research-intermittent-fasting-shows-health-benefits https://medicalxpress.com/news/2022-10-treatment-pulmonary-fibrosis-focus-telomeres.html https://pubmed.ncbi.nlm.nih.gov/29727683/ https://www.nejm.org/doi/full/10.1056/NEJMc2001176 https://pubmed.ncbi.nlm.nih.gov/23408502/ https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30605-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276518306051%3Fshowall%3Dtrue https://www.clinicaltrials.gov/ct2/show/NCT04375657 https://pubmed.ncbi.nlm.nih.gov/7714088/ https://pubmed.ncbi.nlm.nih.gov/6859089/ https://pubmed.ncbi.nlm.nih.gov/21410865/ https://pubmed.ncbi.nlm.nih.gov/28235195/ https://www.ncbi.nlm.nih.gov/pubmed/24905167 https://www.ncbi.nlm.nih.gov/pubmed/10859646 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470960/ https://europepmc.org/article/MED/22402737?javascript_support=no https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2265.2005.02288.x https://pubmed.ncbi.nlm.nih.gov/31890243/ https://www.ncbi.nlm.nih.gov/pubmed/10232622 This list compiled over years of research by the user known as Pottenger's Human on youtube but feel free to copy and paste this anywhere you like, no accreditation needed! My channel which will always contain an updated version of this list of fasting benefits on the community tab. I also have playlists on fasting and health topics.

Dr. J.performored a miraculous intervention on me in the cath lab. He is a tremendous human being. His skill as a cardiologist is extrordinary and the information that he delivers is very accurate

Thank you, Dr. Pradip Jamnadas, I first started listening to you On March 9th, 2023. I followed all of the information you spoke about in your videos. March I was 318 pounds, today April 12, 2023, My weight is 290 pounds. I have reduced 28 to almost 30 pounds gone. You spoke about Fasting, and this is what I am doing, and pushing more Raw and vegan eating. I have been online and found so mean recipes, eating bone broth and vegetable broth, I also made the Lentil bread ( with 2 ingredients) and I love the way my healthy lifestyles. Thank you for helping me.

Wouldn't we all love to have a doctor like this?!!!

Best explanation of the vagus nerve I have come across. Our health is in our diet, and therefore largely in our own hands. Thank you for all you do Doc.

I believe he is the only cardiologist working with gut health to fix your health.

4 months ago, around there, I commented that I had maintained at 280 lbs since high school (7 years ago) and that I had been on OMAD since high school but I just maintained the weight. I’ve been married going on 5 years and 4 months ago when I commented I said I was down to 250! I weighed myself just a few minutes ago and I’m down to 217!!!! Just work! Discipline!! WHOLE FOODS NOT THE STROE BUT WHOLE FOODS!!!!! Eat less and less often!!! Move around more, try to get in 10,000 steps a day or at least 5,000!!! It takes time but it works!!!

I am on my 3rd day of Fasting since watching Dr Jamnadas and Dr Fung . First two day was a bit of a struggle and I did cheat a teeny bit ; eating a odd date or two to get over my junky moments . My gut and the whole GI TRACT already feels so calm and no pains (IBS) and unpleasant toilet experiences. It’s totally easier ones I understood the biology , physiology and all the allied facts , of how why ,what and how the GI functions . I sleep soundly ¬ dreaded the pains , during and after bowel movement . No pains means the world to me and I am grateful to you . Thank you and respect . (I am 64 yr olde retired nurse abd suffered from my bowel for 4 decades ). I can now see my way forward .

Sir for lots of people like me, these videos are worth millions dollar. Please continue the series 🙏🔥 I also request you to make vagus nerve connections full video after gut bacteria series is comepleted. This videos are really helpful where most of people sufferred from gut problems after covid. Thank you so much sir🙏

Thanks Dr. J for another breakthrough video. You’ve opened up a whole new vista of understanding of how our intelligent bodies work and how we can aid that intelligence to achieve better health and fuller lives.

Great video. I love how you've explained the connection between gut microbiome heath and vasal nurological disorders.

Thank you so much. My son was diagnosed with vaso vagal syncope when he was young. I have never really understood the issue until just now when watching your video. Thank you for making this information free to us. Thank you for caring so much about our health.

You open up all the connections to everything medically in our body and for us to understand and apply to our lives which is healthy living. We have responsibilities to our own body and you just helped millions of people and growing. Thank you for sharing your knowledge 🙏

If you are reading this there’s a reason……No matter how good or bad you have it,wake up each day thankful for your life.Someone somewhere else is desperately fighting for theirs ❤️🇧🇸

I very much wish more medical professionals displayed the obvious passion for actual health, and getting to the ROUTE cause and less treating surface symptoms as yourself. Thank you please keep at it because the medical 'industry' needs a long overdue overhaul. I always absolutely love your videos and your outstanding enthusiasm and I even send some to my Mother, as obviously I want her to understand the important of nutrition.

I like Dr. Pradip; he explains issues quite well. Wish we had more docs like him.

For me it all started with 2 videos - The Bittersweet Truth and then The Fat Lies. I changed over night and never looked back. These 2 videos changed how I think. I now only eat whole natural human food. And I do human behavior. No sugars, no seed oils, no processed foods, no carbs and no chemicals. Only whole human food. The rest is good sleep, plenty of sunshine, movement, OMAD and IF. Autophagy and Ketones are normal human behavior.

Just look at him his skin is so flawless that to me is a picture of health in itself ! Doc your the best thankyou for all you do for us 🙏🏻

You are just fantastic. As a DC I share your videos with all my patient. Thank you.